Dataset | set03_wtNotch_versus_normalThy |
Phenotype | NoPhenotypeAvailable |
Upregulated in class | na_neg |
GeneSet | INOH_POSITIVE REGULATION OF (TRANSCRIPTION OF SOCS BY STAT DIMER) IN JAK STAT PATHWAY |
Enrichment Score (ES) | -0.50382125 |
Normalized Enrichment Score (NES) | -1.82882 |
Nominal p-value | 0.0024752475 |
FDR q-value | 0.09390347 |
FWER p-Value | 0.843 |
PROBE | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
---|---|---|---|---|---|---|---|
1 | CCNH | 394 | 3.944 | -0.0070 | No | ||
2 | CDK4 | 450 | 3.776 | 0.0038 | No | ||
3 | MAPKAPK2 | 468 | 3.735 | 0.0165 | No | ||
4 | STAT5A | 573 | 3.481 | 0.0235 | No | ||
5 | RIPK1 | 687 | 3.202 | 0.0290 | No | ||
6 | PDGFRB | 718 | 3.142 | 0.0389 | No | ||
7 | PTK2 | 791 | 3.028 | 0.0460 | No | ||
8 | RPS6KA1 | 1191 | 2.561 | 0.0337 | No | ||
9 | FLT4 | 1254 | 2.501 | 0.0395 | No | ||
10 | RPS6KA3 | 1667 | 2.178 | 0.0251 | No | ||
11 | FGFR3 | 1889 | 2.045 | 0.0206 | No | ||
12 | TYK2 | 2086 | 1.942 | 0.0170 | No | ||
13 | JAK3 | 2330 | 1.824 | 0.0105 | No | ||
14 | FLT1 | 2437 | 1.773 | 0.0113 | No | ||
15 | PRKAR2A | 2477 | 1.752 | 0.0155 | No | ||
16 | IRAK4 | 2882 | 1.584 | -0.0006 | No | ||
17 | RYK | 2944 | 1.559 | 0.0018 | No | ||
18 | PRKAR2B | 3314 | 1.426 | -0.0130 | No | ||
19 | LTK | 3507 | 1.362 | -0.0184 | No | ||
20 | RIPK3 | 3560 | 1.346 | -0.0163 | No | ||
21 | FGFR4 | 3959 | 1.225 | -0.0334 | No | ||
22 | PRKCD | 4150 | 1.173 | -0.0394 | No | ||
23 | PRKACA | 4799 | 1.014 | -0.0708 | No | ||
24 | RPS6KA2 | 4865 | 0.998 | -0.0707 | No | ||
25 | FGFR2 | 4949 | 0.981 | -0.0716 | No | ||
26 | MAP3K7 | 5000 | 0.970 | -0.0708 | No | ||
27 | MAPK10 | 5114 | 0.942 | -0.0734 | No | ||
28 | MAPKAPK5 | 5303 | 0.891 | -0.0804 | No | ||
29 | PDGFRA | 5317 | 0.887 | -0.0778 | No | ||
30 | MAP2K4 | 5861 | 0.762 | -0.1045 | No | ||
31 | PLK1 | 6008 | 0.731 | -0.1097 | No | ||
32 | IRAK1 | 6113 | 0.708 | -0.1127 | No | ||
33 | MAPK13 | 6168 | 0.698 | -0.1131 | No | ||
34 | CAMK2A | 6209 | 0.688 | -0.1128 | No | ||
35 | FGFR1 | 6252 | 0.677 | -0.1126 | No | ||
36 | PAK4 | 6365 | 0.653 | -0.1163 | No | ||
37 | CAMK2G | 6527 | 0.623 | -0.1227 | No | ||
38 | RPS6KB2 | 6565 | 0.616 | -0.1225 | No | ||
39 | CAMK2B | 6676 | 0.594 | -0.1263 | No | ||
40 | AKT1 | 6886 | 0.551 | -0.1356 | No | ||
41 | MOS | 7341 | 0.456 | -0.1585 | No | ||
42 | PRKCA | 7407 | 0.444 | -0.1604 | No | ||
43 | CDK7 | 7589 | 0.409 | -0.1687 | No | ||
44 | MAP2K2 | 7680 | 0.391 | -0.1721 | No | ||
45 | BMPR2 | 8099 | 0.304 | -0.1936 | No | ||
46 | ACVR2A | 8372 | 0.250 | -0.2074 | No | ||
47 | PRKCZ | 8446 | 0.236 | -0.2105 | No | ||
48 | BMPR1A | 8786 | 0.166 | -0.2283 | No | ||
49 | CHUK | 9136 | 0.102 | -0.2468 | No | ||
50 | MAP2K1 | 9431 | 0.042 | -0.2625 | No | ||
51 | ACVR1 | 9653 | -0.003 | -0.2745 | No | ||
52 | BTK | 9731 | -0.016 | -0.2786 | No | ||
53 | ACVRL1 | 10103 | -0.091 | -0.2983 | No | ||
54 | PAK3 | 10206 | -0.112 | -0.3034 | No | ||
55 | KDR | 10240 | -0.118 | -0.3048 | No | ||
56 | NGFR | 10479 | -0.163 | -0.3171 | No | ||
57 | MAP2K3 | 10511 | -0.169 | -0.3181 | No | ||
58 | SRC | 11366 | -0.352 | -0.3630 | No | ||
59 | PRKAR1B | 11568 | -0.397 | -0.3725 | No | ||
60 | GFRA1 | 11706 | -0.429 | -0.3783 | No | ||
61 | MAPK3 | 11722 | -0.435 | -0.3775 | No | ||
62 | WEE1 | 11945 | -0.478 | -0.3878 | No | ||
63 | MKNK2 | 12122 | -0.517 | -0.3955 | No | ||
64 | PRKCE | 12144 | -0.521 | -0.3947 | No | ||
65 | IKBKB | 12258 | -0.546 | -0.3988 | No | ||
66 | PRKG1 | 12437 | -0.589 | -0.4063 | No | ||
67 | ZAP70 | 12681 | -0.648 | -0.4171 | No | ||
68 | CDK6 | 12685 | -0.649 | -0.4149 | No | ||
69 | MAPK7 | 12748 | -0.663 | -0.4158 | No | ||
70 | KIT | 13043 | -0.731 | -0.4291 | No | ||
71 | EGFR | 13064 | -0.736 | -0.4275 | No | ||
72 | PRKCI | 13267 | -0.791 | -0.4355 | No | ||
73 | PRKG2 | 13555 | -0.861 | -0.4479 | No | ||
74 | MNAT1 | 13580 | -0.869 | -0.4461 | No | ||
75 | PAK2 | 13592 | -0.871 | -0.4435 | No | ||
76 | JAK1 | 13695 | -0.897 | -0.4457 | No | ||
77 | MET | 13922 | -0.967 | -0.4545 | No | ||
78 | GRK6 | 14305 | -1.077 | -0.4712 | No | ||
79 | ALK | 14320 | -1.081 | -0.4680 | No | ||
80 | MAP3K2 | 14359 | -1.091 | -0.4661 | No | ||
81 | TGFBR1 | 14475 | -1.126 | -0.4682 | No | ||
82 | ARAF | 14504 | -1.136 | -0.4656 | No | ||
83 | CSK | 14774 | -1.225 | -0.4757 | No | ||
84 | PAK1 | 14871 | -1.265 | -0.4763 | No | ||
85 | MAPK8 | 15028 | -1.330 | -0.4799 | No | ||
86 | MAPK14 | 15392 | -1.490 | -0.4941 | No | ||
87 | MAPK12 | 15410 | -1.504 | -0.4896 | No | ||
88 | STAT5B | 15505 | -1.559 | -0.4890 | No | ||
89 | JAK2 | 15518 | -1.569 | -0.4839 | No | ||
90 | RIPK2 | 15887 | -1.764 | -0.4974 | Yes | ||
91 | MAP3K5 | 15909 | -1.779 | -0.4921 | Yes | ||
92 | RAF1 | 15947 | -1.805 | -0.4875 | Yes | ||
93 | BMPR1B | 15980 | -1.831 | -0.4826 | Yes | ||
94 | SYK | 16044 | -1.873 | -0.4792 | Yes | ||
95 | NLK | 16066 | -1.886 | -0.4734 | Yes | ||
96 | MAP3K1 | 16099 | -1.908 | -0.4682 | Yes | ||
97 | MAP3K14 | 16110 | -1.919 | -0.4618 | Yes | ||
98 | INSR | 16269 | -2.034 | -0.4629 | Yes | ||
99 | ACVR2B | 16359 | -2.103 | -0.4601 | Yes | ||
100 | PRKCH | 16424 | -2.159 | -0.4557 | Yes | ||
101 | MKNK1 | 16480 | -2.203 | -0.4507 | Yes | ||
102 | AKT2 | 16584 | -2.289 | -0.4479 | Yes | ||
103 | PLK3 | 16606 | -2.308 | -0.4406 | Yes | ||
104 | LCK | 16851 | -2.559 | -0.4445 | Yes | ||
105 | MAP3K11 | 16964 | -2.684 | -0.4408 | Yes | ||
106 | CDK2 | 17094 | -2.849 | -0.4374 | Yes | ||
107 | MAPK9 | 17129 | -2.896 | -0.4287 | Yes | ||
108 | GSK3B | 17139 | -2.906 | -0.4187 | Yes | ||
109 | PRKCQ | 17373 | -3.270 | -0.4194 | Yes | ||
110 | IGF1R | 17477 | -3.463 | -0.4123 | Yes | ||
111 | MAP4K3 | 17566 | -3.626 | -0.4039 | Yes | ||
112 | MAP3K8 | 17644 | -3.789 | -0.3943 | Yes | ||
113 | STAT4 | 17687 | -3.878 | -0.3824 | Yes | ||
114 | CDK5 | 17776 | -4.065 | -0.3724 | Yes | ||
115 | MAP3K12 | 17778 | -4.065 | -0.3577 | Yes | ||
116 | IKBKG | 17782 | -4.070 | -0.3430 | Yes | ||
117 | FYN | 17854 | -4.233 | -0.3315 | Yes | ||
118 | MAPK11 | 17912 | -4.438 | -0.3184 | Yes | ||
119 | MAP2K6 | 17919 | -4.460 | -0.3025 | Yes | ||
120 | STAT3 | 17998 | -4.700 | -0.2896 | Yes | ||
121 | MAP3K3 | 18061 | -4.882 | -0.2752 | Yes | ||
122 | STAT2 | 18166 | -5.430 | -0.2611 | Yes | ||
123 | IKBKE | 18185 | -5.485 | -0.2421 | Yes | ||
124 | PDPK1 | 18265 | -5.919 | -0.2248 | Yes | ||
125 | CSNK1E | 18290 | -6.103 | -0.2039 | Yes | ||
126 | TGFBR2 | 18307 | -6.182 | -0.1823 | Yes | ||
127 | STAT1 | 18408 | -7.085 | -0.1619 | Yes | ||
128 | MAP4K2 | 18412 | -7.157 | -0.1361 | Yes | ||
129 | AKT3 | 18419 | -7.198 | -0.1102 | Yes | ||
130 | ITK | 18446 | -7.525 | -0.0842 | Yes | ||
131 | PTK2B | 18539 | -9.957 | -0.0530 | Yes | ||
132 | TEC | 18587 | -15.689 | 0.0016 | Yes |